Under the same conditions that I ran it's a significant difference, roughly 12k damage difference. But yes, big difference.
main="Caladbolg",
sub="Utu Grip",
ranged=Empty,
ammo="Knobkierrie",
head="Nyame Helm",
body="Nyame Mail",
hands="Nyame Gauntlets",
legs="Fall. Flanchard +4",
feet="Heath. Sollerets +3",
neck="Abyssal Beads +2",
waist="Sailfi Belt +1",
ear1="Moonshade Earring",
ear2="Thrud Earring",
ring1="Epaminondas's Ring",
ring2="Niqmaddu Ring",
back="Ankou's Mantle",
SV songs with Aria on cogs, lucky chaos/sam cor rolls(no XI but gave job bonus), Dia 3 with light shot, warcry from war, boost-str, sublime sushi +1 because DRK can't hit a barn door with a shovel, and distract 3. The above set punched out ~73k at 1ktp spam. Replacing only calad with ragnarok punched out ~61k. (Nyame was set to path b r25)
I ran it like this because trash mobs be trash and I run it on the higher level cogs because it's somewhat more (albeit not really) similar to say sortie basement bosses from an acc perspective and at least its a higher stats compared to in order to better understand making use of pdl or other. No armor break or geo as GEO may or may not even be present half the time, and armor break may or may not even land so that's entirely dependent on resistances and macc.
Was thinking from a practical standpoint of perhaps a melee sortie run with WAR,DRK,BRD,COR,RDM,WHM.