:To is not a very good brew WS under normal conditions. The hybrid nature of it allows for great numbers with double/triple attacks, though. I wouldn't recommend this really, it's unreliable and averages lower than wildfire/edge/good physical ws.
However, if you go THF/NIN with a
trainee burin, you can SA :To for an essentially guaranteed one shot. Razed Ruins/Beyond/Smiting Blow. It's been a while and I'm pretty sure you're fine with no gear, but AF3+2 hands, breeze gorget/belt, and any crit damage+% should add a decent chunk if needed.
Depending on fight style, this might or not be practical. If you're locking down by the flux and pulling azdajas there every 15 min(just doing deelgeed with a lock), you could kill near/exactly thirty pops on one brew(6 sec to SA WS and relock * 30 = 3 minutes).
If you're cleaving pops or even have amber built single targeting, the time spent running all the way down there'll add up. Waiting a full minute for SA will add up. Locking by the spawn can be messy, though if you coordinate well its certainly doable to sneak the THF as it dies so they can lock on a chest and still get a decent amount of kills in. This'll reduce the # vs a.edge(though I imagine it'd still win by a lot).
It pretty much comes down to how much you value cruor, how many people you have, and what jobs are available. If you're amber farming and have spare cruor/bodies, edge killing 5+ at a time will get it done faster, it'll just cost more brews.